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View Poll Results: Which jab have you had? | |||
Pfizer | 53 | 51.96% | |
Moderna | 27 | 26.47% | |
Johnson & Johnson | 6 | 5.88% | |
AstraZeneca | 4 | 3.92% | |
Novavax | 0 | 0% | |
Sputnik | 1 | 0.98% | |
Convidecia | 0 | 0% | |
Homebrew with a big dose of something special | 11 | 10.78% | |
Voters: 102. You may not vote on this poll |
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07-12-2021, 05:44 PM | #3081 |
義理チョコ
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Except that he could be cooking up the next super mutation. :/
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07-12-2021, 06:06 PM | #3082 |
Airborne at your service
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That's inevitable at this point.
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07-12-2021, 07:44 PM | #3083 |
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07-12-2021, 07:45 PM | #3084 | |
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07-12-2021, 07:47 PM | #3085 |
Airborne at your service
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07-12-2021, 09:53 PM | #3086 | ||
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But it does stop you from transmitting it. Vaccinated individuals who test positive for covid are simply NOT shedding enough virus to be a contagious carrier. Let me just say that again: vaccinated people are not transmitting the virus to others. The data is there, research it.
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07-12-2021, 10:56 PM | #3087 | |
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Absent that, it's just more MSU.
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07-12-2021, 11:04 PM | #3088 |
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The minute I received my second fauci ouchie I knew I had arrived and now had the authority to wish I'll health on those who hadn't grabbed the bull by its balls like I did.
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07-12-2021, 11:11 PM | #3089 |
義理チョコ
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Not at all. I'm just disappoint.
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07-12-2021, 11:37 PM | #3090 | |
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07-12-2021, 11:42 PM | #3091 | |
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lol! You are hilarious. I'll leave it at that.
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07-13-2021, 01:46 AM | #3092 |
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WOW! What a lively conversation.
Smallpox had been around for thousands of years and by 1980 it had been eradicated from the earth. How did we do that? This ain't rocket medicine, folks. SMH |
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07-13-2021, 08:08 AM | #3093 |
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Still I cannot see how a pilot, the most probable candidate for point to point transmission all over a country can be allowed to decline vaccination. I am assuming pilot did decline, or perhaps he wishes us to believe he has, in order to keep the thread boiling. Maybe I missed something. There will be no unvaccinated pilots landing into Canada any time soon that's for sure. I am not sure if Canadian commercial air crews are required to be vaccinated. I'm going to guess it's a widely accepted unwritten rule for domestic and of course mandatory for international.
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07-13-2021, 08:56 AM | #3094 | ||
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What strikes all of us is the continued and rapid emergence of progressively more virulent new pathogens. If you read the emerging scientific literature, a potentially worrisome new variant is identified every few weeks. What's most troubling about this is the trend to progressively increasing transmissibility, virulence, and resistance to vaccine-elicited antibodies. None of this is surprising. This is what viruses do. Life mutates and evolves in ways to promote its own survival. With the SARS-CoV-2 virus, that's often at our expense. It's the sheer numbers driving this. Very rough numbers, about half a million new COVID infections worldwide are confirmed daily. This is of course a gross under-estimate, call it a million a day to make it easy. Thus, roughly 20 million new infections every 20 days, about how often a new variant is identified. That's a lot of mutation factories (20 million infected people produce roughly 200 billion new mutations), and it doesn't take a supercomputer to extrapolate where this is going and where we could be in a few years. The emerging variants are showing increasingly reduced susceptibility to vaccine-elicited antibodies. Many of them are 3-8 fold less susceptible to neutralization by antibodies in the blood of vaccinated individuals. https://www.biorxiv.org/content/10.1....full.pdf+html https://www.sciencedirect.com/scienc...92867421002981 This is a problem, because when the level of antibodies it takes to neutralize a variant exceeds what's in your blood, you can have breakthrough infections - as has already been shown with the Delta B.1.617.2, Beta B.1.35, and Gamma P.1 variants. https://www.medrxiv.org/content/10.1....06.21254882v1 https://www.gov.il/en/departments/news/05072021-03 The variants are accumulating multiple mutations in the 'spike' region. Again this is not at all surprising, since this is the mechanism by which the virus infects our cells. Become more efficient and effective at infecting our cells, and it promotes its own survival. Another new variant recently described is Lamba (C.37) https://www.livescience.com/lambda-c...s-variant.html It contains 7 mutations in the spike region, including one, F490S, that a recent study says may be a ‘vaccine escape mutation’ https://www.sciencedirect.com/scienc...88754321001798 The laws of evolution dictate that this will continue. New variants will emerge that are more easily transmitted, cause more serious disease (by multiplying more quickly) https://virological.org/t/viral-infe...-2-variant/724 and are increasingly less susceptible to vaccine-elicted antibodies, because those traits enhance it's survival. Unfortunately, those characteristics come at our expense. The concern is that variants are emerging so quickly that we'll get to the point where we can't keep ahead of them, even with 'booster' shots. Pfizer is catching flak right now for coming out with a recommendation for booster shots. Yes, big pharma companies are greedy scum and want to make as much money as possible. But their recommendations are based on solid science and work done by many groups - to neutralize Delta you need a higher level of antibodies https://www.biorxiv.org/content/10.1....full.pdf+html and antibody levels decline over time (especially in certain populations, such as the elderly). We're already seeing reduced vaccine effectiveness against Delta - it's a logical proposal to boost antibody levels with the vaccine we already have. Yes, vaccines can be tweaked and clinical study is already underway with a modified version designed to be more active against Delta. But it takes time. Even if it were possible to do the work in half the time of the original vaccine, in 6 months we are likely to have several new variants spreading (like Lambda). We might not be able to stay ahead of it. This is why I suggest that over the long term, the pandemic may well be a decimation or extinction level event (pick your favorite term) for the unvaccinated. Just like the bubonic plagues in the Middle Ages are thought to have killed half of Europe's population (until the survivors did the only thing they could, a hard lockdown)(which still works today), I suspect the numbers of unvaccinated people will dwindle over time. It's their choice. Call me crazy (and lots of people have called me far worse), but I'd rather choose life. |
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