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Old 08-30-2021, 10:52 AM   #519
AnalogMan
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Quote:
Originally Posted by MuseChaser View Post
The increasing number of doctors PRESCRIBING ivermectin indicates that ivermectin has, indeed, shown some efficacy in alleviating Covid symptoms.
Or, another possible explanation might be that some doctors will prescribe anything for money or give patients whatever they want, medically justified or not (but of course that never happens, and especially not in Florida).

https://www.healthline.com/health-ne...pioid-epidemic

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3030470/

This is a recently published meta-analysis of 29 randomized, controlled clinical trials of ivermectin in the treatment of COVID-19. The authors conclude, "The certainty of the evidence was very low to low."

https://www.medrxiv.org/content/10.1....19.21262304v1

This is another meta-analysis of 10 ivermectin clinical trials. The authors conclude "IVM did not reduce all-cause mortality, length of stay or viral clearance in RCTs in COVID-19 patients with mostly mild disease. IVM did not have effect on AEs or SAEs. IVM is not a viable option to treat COVID-19 patients."

https://www.medrxiv.org/content/10.1....21.21257595v2

Yet one more meta-analysis of 12 clinical trials of ivermectin in the treatment of COVID-19. The authors conclude, "Ivermectin was not associated with reduced mortality, or reduced patient recovery. All studies had a high risk of bias, and showed a very low certainty of the evidence."

https://www.medrxiv.org/content/10.1....26.21250420v1

Over the past 35 years, I've overseen or worked on clinical programs for 16 different therapeutic drugs. One can always torture data, play statistical games, or inadvertently (or intentionally) introduce bias that can skew outcomes. Desperation to find treatments for dire conditions can also be a factor. Which is why the above meta-analyses examining all of the trials to date are particularly interesting.

Your mileage may vary.
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