That all seems normal. If the ethanol content changes, the tune will adjust for it. the fuel trims might look a little off until it does so. Unless you're seeing over +/-10%, you're fine.
The MPG reading doesn't change, as I don't think it's actually calculated on fuel used.
https://www.ft86club.com/forums/showthread.php?t=74754
More E85 info bits:
https://www.ft86club.com/forums/showthread.php?t=67310