Not too long after getting the FR-S I took a road trip where I knew I was able to fill-up, hit the highway, and calculate my average speed based on mileage and time. These were the results (documented
here, along with what happens when you use the FR-S as a soapbox derby car):
08/14/2012: 270.50 Miles, 33.08MPG Highway Calculated Avg Speed 72.4 MPH
08/16/2012: 276.50 Miles, 31.60MPG Highway Calculated Avg Speed 73.2 MPH
I later took a similar trip on a different (less elevation change) road and got this, although I didn't calculate the average speed as precisely. This trip (documented here) included 45 minutes of bumper to bumper traffic as well:
12/14/2012: 395.20 Miles, 35.60MPG Highway Speeds (70+MPH)